EXPERIENCE

SKILLS

PUBLICATIONS

• Hegner, B., Schaub T., Catar R., Kusch A.,Wagner P., Essin K., Lange C., Riemekasten G., and D. Dragun, Intrinsic deregulation of vascular smooth muscle and myofibroblast differentiation in mesenchymal stromal cells from patients with systemic sclerosis. PloSOne, 2016. 11(4):e0153101. (Hegner_B_PlosOne_2016.pdf)

• Essin, K. and M. Gollasch, Role of ryanodine receptor subtypes in initiation and formation of calcium sparks in arterial smooth muscle: comparison with striated muscle. J Biomed Biotechnol, 2009. 2009: p. 135249. (Essin_K_JBB_2009.pdf)

• Hegner, B., M. Lange, A. Kusch, K. Essin, O. Sezer, E. Schulze-Lohoff, F.C. Luft, M. Gollasch, and D. Dragun, mTOR regulates vascular smooth muscle cell differentiation from human bone marrow-derived mesenchymal progenitors. Arterioscler Thromb Vasc Biol, 2009. 29(2): p. 232-8. (Hegner_B_ATVB_2009.pdf)

• Essin, K., M. Gollasch, S. Rolle, P. Weissgerber, M. Sausbier, E. Bohn, I.B. Autenrieth, P. Ruth, F.C. Luft, W.M. Nauseef, and R. Kettritz, BK channels in innate immune functions of neutrophils and macrophages. Blood, 2009. 113(6): p. 1326-31. (Essin_K_Blood_2009.pdf)

• Mederos y Schnitzler, M., U. Storch, S. Meibers, P. Nurwakagari, A. Breit, K. Essin, M. Gollasch, and T. Gudermann, Gq-coupled receptors as mechanosensors mediating myogenic vasoconstriction. EMBO J, 2008. 27(23): p. 3092-103. (Mederos_y_Schnitzler_EMBO_2008.pdf)

• Muller, M., K. Essin, K. Hill, H. Beschmann, S. Rubant, C.M. Schempp, M. Gollasch, W.H. Boehncke, C. Harteneck, W.E. Muller, and K. Leuner, Specific TRPC6 channel activation, a novel approach to stimulate keratinocyte differentiation. J Biol Chem, 2008. 283(49): p. 33942-54. (Mueller_M_JBC_2008.pdf)

• Hercule, H.C., B. Salanova, K. Essin, H. Honeck, J.R. Falck, M. Sausbier, P. Ruth, W.H. Schunck, F.C. Luft, and M. Gollasch, The vasodilator 17,18-epoxyeicosatetraenoic acid targets the pore-forming BK alpha channel subunit in rodents. Exp Physiol, 2007. 92(6): p. 1067-76. (Hercule_HC_ExpPhys_2007.pdf)

• Essin, K., A. Welling, F. Hofmann, F.C. Luft, M. Gollasch, and S. Moosmang, Indirect coupling between Cav1.2 channels and ryanodine receptors to generate Ca2+ sparks in murine arterial smooth muscle cells. J Physiol, 2007. 584(Pt 1): p. 205-19. (Essin_K_JPhys_2007.pdf)

• Leuner, K., V. Kazanski, M. Muller, K. Essin, B. Henke, M. Gollasch, C. Harteneck, and W.E. Muller, Hyperforin - a key constituent of St. John's wort specifically activates TRPC6 channels. FASEB J, 2007. 21(14): p. 4101-11. (Leuner_K_FASEB_2007.pdf)

• Dietrich, A., H. Kalwa, U. Storch, M. Mederos y Schnitzler, B. Salanova, O. Pinkenburg, G. Dubrovska, K. Essin, M. Gollasch, L. Birnbaumer, and T. Gudermann, Pressure-induced and store-operated cation influx in vascular smooth muscle cells is independent of TRPC1. Pflugers Arch, 2007. 455(3): p. 465-77. (Dietrich_A_PflArch_2005.pdf)

• Essin, K., B. Salanova, R. Kettritz, M. Sausbier, F.C. Luft, D. Kraus, E. Bohn, I.B. Autenrieth, A. Peschel, P. Ruth, and M. Gollasch, Large-conductance calcium-activated potassium channel activity is absent in human and mouse neutrophils and is not required for innate immunity. Am J Physiol Cell Physiol, 2007. 293(1): p. C45-54. (Essin_K_AJP_2007.pdf)

• Dietrich, A., Y.S.M. Mederos, M. Gollasch, V. Gross, U. Storch, G. Dubrovska, M. Obst, E. Yildirim, B. Salanova, H. Kalwa, K. Essin, O. Pinkenburg, F.C. Luft, T. Gudermann, and L. Birnbaumer, Increased vascular smooth muscle contractility in TRPC6-/- mice. Mol Cell Biol, 2005. 25(16): p. 6980-9. (Dietrich_A_MolCellBiol_2005)

• Sausbier, M., C. Arntz, I. Bucurenciu, H. Zhao, X.B. Zhou, U. Sausbier, S. Feil, S. Kamm, K. Essin, C.A. Sailer, U. Abdullah, P. Krippeit-Drews, R. Feil, F. Hofmann, H.G. Knaus, C. Kenyon, M.J. Shipston, J.F. Storm, W. Neuhuber, M. Korth, R. Schubert, M. Gollasch, and P. Ruth, Elevated blood pressure linked to primary hyperaldosteronism and impaired vasodilation in BK channel-deficient mice. Circulation, 2005. 112(1): p. 60-8. (Sausbier_M_Circulation_2005.pdf)

• Verlohren, S., G. Dubrovska, S.Y. Tsang, K. Essin, F.C. Luft, Y. Huang, and M. Gollasch, Visceral periadventitial adipose tissue regulates arterial tone of mesenteric arteries. Hypertension, 2004. 44(3): p. 271-6. (Verlohren_S_Hypertension_2004.pdf)

• Tsang, S.Y., X. Yao, K. Essin, C.M. Wong, F.L. Chan, M. Gollasch, and Y. Huang, Raloxifene relaxes rat cerebral arteries in vitro and inhibits L-type voltage-sensitive Ca2+ channels. Stroke, 2004. 35(7): p. 1709-14. (Tsang_SY_Stroke_2004.pdf)

• Wernicke, D., C. Thiel, C.M. Duja-Isac, K.V. Essin, M. Spindler, D.J. Nunez, R. Plehm, N. Wessel, A. Hammes, R.J. Edwards, A. Lippoldt, U. Zacharias, H. Stromer, S. Neubauer, M.J. Davies, I. Morano, and L. Thierfelder, alpha-Tropomyosin mutations Asp(175)Asn and Glu(180)Gly affect cardiac function in transgenic rats in different ways. Am J Physiol Regul Integr Comp Physiol, 2004. 287(3): p. R685-95. (Wernicke_D_AJP_2004.pdf)

• Essin, K., A. Nistri, and L. Magazanik, Evaluation of GluR2 subunit involvement in AMPA receptor function of neonatal rat hypoglossal motoneurons. Eur J Neurosci, 2002. 15(12): p. 1899-906. (Essin_K_EurJNeurosci_2002.pdf)

• Lohn, M., U. Muzzulini, K. Essin, S.Y. Tsang, T. Kirsch, J. Litteral, P. Waldron, H. Conrad, N. Klugbauer, F. Hofmann, H. Haller, F.C. Luft, Y. Huang, and M. Gollasch, Cilnidipine is a novel slow-acting blocker of vascular L-type calcium channels that does not target protein kinase C. J Hypertens, 2002. 20(5): p. 885-93.

• Bolshakov, K.V., K.V. Essin, S.L. Buldakova, N.A. Dorofeeva, S.N. Skatchkov, M.J. Eaton, D.B. Tikhonov, and L.G. Magazanik, Characterization of acid-sensitive ion channels in freshly isolated rat brain neurons. Neuroscience, 2002. 110(4): p. 723-30. (Bolshakov_KV_Neuroscience_2002.pdf)

• Magazanik, L.G., M.V. Samoilova, S.L. Buldakova, K.V. Esin, and V.E. Gmiro, Selective block of AMPA/kainate receptors of hippocampal interneurons as a new approach to the investigation of inhibitory system. Ross Fiziol Zh Im I M Sechenova, 1997. 83(5-6): p. 19-39. (Magazanik_LG_RossFiziolZh_1997.pdf)

AWARDS

• Phoenix Pharmazie-Wissenschaftpreis fuer die innovativ-qualitativ hervorragende wissenschaftliche Arbeit auf dem Gebiet Pharmakologie, Freiburg, Germany 2008
• Young scientist award, 26th scientific congress on hypertension, Dresden, Germany 2002
• Young scientist award, congress of young scientists, St. Petersburg, Russia, 1998
• First honors class diploma, St. Petersburg State University, Russia, 1993